Caryophyllene,. It is a Marijuana Terpene used in the Perfume industry to give things a Marijuana smell, and recently I learned that it actually connects with the CB2 (Cannabinoid) receptor, even without any Cannabinoiids. So Caryophyllene has cannabis effects, even when taken outside or without Cannabis. Sources of Carryophyllene include Uziza Pepper 50% of Essential oil) and Indian Bay Leaves (25% of Essential Oil). So taking either of these things can and will increase the effects of the Cannabinoids.
Indole-3-Carbinol can be found in many common vegetables, and it breaks down to activate the CB2 receptor.
Common Rue Essential Oil activates the CB2 receptor.
I also learned more about Hash making. Remember when I said that you
could use the Concrete making method and the Absolute making method from
Dr. Atomic and the Perfume world? Well, there are steps you can take
after that to ensure that your Cannabinoids are the BEST they can be.
you do just like before. Using Lemonene or some other non-Polar
solvent, make your Cannabis extract. Then add some kind of Alcohol
(Ethanol, Isopropyl or Methanol) let that sit and eventually the
Lemonene and Alcohol will separate. Use a Separatory funnel to separate
these layers. St this point you have Cannabis absolute, aka medical
grade hash in alcohol.
If you add a few drops of Sulfuric acid at
this time, all the Cannabinoids will turn into THC Cannabinoids, and
all the THC cannabinoids will become pure Delta-9-THC. That method was
in the Dr. Atiomic book, I just did not add it before.
There are 2 other methods you can use at this point that I recently found out about.
you have the medical grade hash, you can treat it with Acetic Acid
instead of Sulfuric acid, and this will make THC-0-Acetate, which is a
little bit stronger than THC.
or, You can extract the THC in
Pyridine instead of alcohol, the add Phosphoryl Chloride, this will make
THC-O-Phosphate which is weaker than THC, but can be used in hospitals
easier, because it is water soluble which makes it injectable.
will stop here now because I have made a wall of text, but I have been
doing research for like 2 straight days with only like 8 hours of sleep
total. So I can continue with this in a few days or weeks.
I decided not to wait a few days or weeks, I am going to continue the Chemistry stuff now.
I was researching Nootropics a while ago I found what is called
"Picamilon", this is a Nootropic which you can buy in America and they
actually prescribe it to people in Russia. What it is is GABA powder and
Niacin powder, these are both Amino Acids so they both have the
properties of both an acid and a base depending on the situation. So
during my research over the past few days, I decided to find out how
Picamilon is made, and I found something out that may lead to some new
Nootropics. Picamilon is just about the easiest Chemical reaction in the
world. From what I learned, when you mix to Amino Acids together and
apply heat, they will release H20 and form what is called a "Peptide
Bond". So simply by putting GABA powder and Niacin powder in water (in
equal amounts) and evaporating all the water away, you are creating
"Picamilon". This substance has the ability to cross the blood brain
barrier better than regular GABA, so it has a much stronger effect on
those receptors. But it's not hard to make at all. So I am going to make
some of that, and then maybe get some other Amino Acids and see what
happens. Usually people wouldn't "invent" new molecules and eat them,
but I am following in the footsteps of Sasha Shulgin. I will get some
Amino Acids sometime in the next month or 2. Oilahuasca and Marijuasca
I will continue this again later with Hydrogen Bonds and stuff.
just want to say something that might help people understand this
better. And I will help people understand even more when I get into the
bonds. But if you want to understand Chemistry at its most BASIC, here
is a good thought exercise.
First, accept that Chemical reactions
are all just Magnets figuring out what they are attracted to. Chemistry
is ALL ABOUT magnets, everything is polar or non-polar, acid or base,
etc. and these things are basically all just magnetic responses that
chemicals have to each other.
Now, understanding that it is all
about Magnets, let's make it more clear with an example. Water. H2O. If
you were to take 1 Hydrogen from H2O, suddenly it would be Hydroxide
which is pretty much the STRONGEST most reactive base known to man. If
you add a Hydroxide material (ex: Calcium Hydroxide) to water, the
Hydrogen in the water becomes charged with a negative polarity and can
be used to do things like extractions or pickling. Acids are the
opposite of that. their Hydrogen is positively charged and is waiting
connect to some other molecule. Acids usually have lots of Oxygen ready
to attach magnetically to Hydrogen, Hydroxide or Hydrocarbons. If you
add an acid to water, it charges the hydrogen in the water with a
positive charge, and this can be used for extractions or as cleaning
And when an acid and a base come together, they form a
salt. Salts are usually neutral. And water is kind of like a salt, since
it is Hydrogen and Oxygen in a higher concentration that in OH
(Hydroxide). It is "acidic" hydrogen mixed with "basic" oxygen. It is
not actually a salt, but noticing what it is made of can help you
understand the magnet concept.
Ok, so as I mentioned before, THC
can be treated with Acetic Acid in order to make THC-O-Acetate which is a
little stronger by weight than THC itself. This can be done with other
things as well. Most people have heard of Heroine and Morphine. Heroine
is the Acetate form of Morphine, some people even make it by using
vinegar which is about 5% acetic acid.
If you have heard of
Choline, it improves brain function and promotes the creation of
"AcetylCholine" in the brain, which is the specific thing that regulates
dreaming. I am not positive, but I am pretty sure that AcetylCholine is
the Acetic Acid treated form of Choline.
I am pretty sure that
this process can be done with other things as well, like Catnip extract
or possibly things like Kava which has similar effects to Marijuana.
Now, let's look at a THC Molecule.
it are a bunch of Hydrocarbons, a Hydroxide and 2 Hydrogens. Meaning,
any Oxygen, Fluorine or Nitrogen could alter it pretty completely. So I
wonder if anyone has ever tried pickling their THC (adding Calcium
Hydroxide aka Edible Lime to it). Or has anyone ever let Marijuana sit
in a Hydrogen Peroxide solution, with maybe an Amino Acid? This could
Change it completely also. Or letting it sit in some kind of Nitrogen
solution. Morpholine is a Nitrogen and Oxygen, when someone adds
morpholine to THC we are going to see some cool new medical
Also, since Marijuana obviously forms
Isomers with Acids (Sulfuric acid and Acetic acid), it might be worth
testing other acids. I am pretty sure no one has ever treated THC with
Tartaric acid, which is used in some medical applications. And I am
almost positive it has never been treated with Malic acid, which is used
in some foods and beverages, as well as occurring naturally.
could have all kinds of different forms that no one has even tried yet.
And I am pretty sure no one has made any kind of 5-MeO-THC or anything
like that yet, and from what I understand all it takes it some Methanol
and something to activate the reaction in order to Methylate the THC
into some X-MeO-form, unless I am mistaken.